Sadio Mane scored twice as African champions Teranga Lions of Senegal beat Brazil 4-2 in a friendly in Lisbon, Portugal.
Brazil have now lost three of their last four games against African teams.
The five-time World Cup champions lost 1-0 to Cameroon in the group stage of the 2022 World Cup in Qatar.
In March this year, they lost 2-1 to Morocco in a friendly game in Tanger.
Just three days ago, the Selecao hammered Guinea 4-1 in another friendly game.
In Tuesday’s friendly with Senegal, West Ham midfielder Lucas Paqueta put Brazil ahead in the 11th minute, before Habib Diallo equalised for Senegal on 22nd minute.
An own goal from Marquinhos in the 52nd minute gave Senegal a 2-1 lead with Mane making it 3-1 in the 57 minutes.
Marquinhos scored in the 58th minute to make it 3-2 before Mane got Senegal’s fourth from the penalty spot