Holders Liverpool will take on Spanish side Atletico Madrid while Manchester City will face Real Madrid in the last 16 of the Champions League.
Chelsea have been drawn against Bayern Munich in a repeat of the 2012 final won by the Blues while Tottenham face RB Leipzig.
In the pick of the other ties, Borussia Dortmund will play Paris St-Germain and Napoli take on Barcelona.
The first legs will be played on 18, 19, 25 and 26 February with the return matches on 10, 11, 17 and 18 March.
This season’s final is on 30 May at the Ataturk Stadium in Istanbul, the ground where Liverpool won the epic 2005 match against AC Milan.
Draws for the Europa League last-32 takes place later on Monday.
Last-16 draw in full
Borussia Dortmund v Paris St-Germain
Real Madrid v Manchester City
Atalanta v Valencia
Atletico Madrid v Liverpool
Chelsea v Bayern Munich
Lyon v Juventus
Tottenham v RB Leipzig
Napoli v Barcelona